• unazebra@lemmy.world
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    1 hour ago

    There’s a testing called genesight that I did through my doctor (so seemingly not sending my DNA to a private company like 23&me) that helped me identify which SSRI would metabolize with the fewest side effects with my specific body chemistry. For those lucky enough to have health insurance, I think insurance will pay for it after 2 attempted SSRIs with bad side effects.

    I wish for rest & gentleness for us all. 🪻🪻

    Genesight

    • jade52@lemmy.ca
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      36 minutes ago

      Holy shit I wish I knew about this like 4 years ago. Would have saved me all the drama of trying each of them out until prozac was the only one that didn’t make me nauseous af

  • teslasaur@lemmy.world
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    2 hours ago

    Started working out, which helped immensely.

    Turns out that sitting inside and looking at doomers is bad for your well-being.

  • Korne127@lemmy.world
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    1 hour ago

    Lose weight? Didn’t know that was supposed to be a thing, I was able to lose 10kg in some months. However, the sexual side effects are real

  • blueamigafan@lemmy.world
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    19 hours ago

    Fuck shit like this, I was having VERY stupid thoughts about ending my existence until my girlfriend dragged me to the doctors, yes there are side effects but the alternative is that otherwise I wouldn’t be here anymore.

    • Victor@lemmy.world
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      18 hours ago

      I think the “joke” is that those side effects would make you very sad as well. Pretty counterproductive to the whole problem itself. 😅

      But hey, I’m very glad you made it out of that state, and your girlfriend sounds like a real keeper. 💖 Keep on trucking! 🙏

  • SourDragon@lemmy.world
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    13 hours ago

    You can’t lose weight, but that’s okay because the lack of appetite balances that out! (A common side effect my antidepressants have)

  • Miller@lemmy.world
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    19 hours ago

    Doc: we are all interested in your bum

    Me: my bum?

    Doc: your bum, we want to stick six feet of hosepipe up there

    Me: I don’t want that to happen

    Doc: expect not, are you free next Tuesday morning?

  • Seth Taylor@lemmy.world
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    20 hours ago

    me: I’m sad

    Local feral cat: Here’s my three kittens. I must go now, my planet needs me

    Vet: This will be expensive and exhausting for you

    Therapist: Pets would be good for you, but you won’t be able to keep up with the necessary work and routines. Maybe at a later time.

    me: Oh yea? I’ll show you! I will attempt to keep up with the necessary work and routines!

    Me again: I failed and broke down immediately

    Still me: gotta give up the cats

    Yet again me: Perfect…

    • some_kind_of_guy@lemmy.world
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      16 hours ago

      For some. If it works for you, you’re lucky. Especially if it’s the first drug you tried.

      For others, depression treatment means bouncing around between different drugs and drug classes until landing on something that works, and doesn’t make things worse. For some people that’s a holy grail that doesn’t actually exist, and they won’t be helped by any of the “traditional” first-line treatments. (The SSRI, SNRI, tricyclic, etc. drugs).

      Some of these take weeks before you even know if it’s working or not. If it doesn’t work, and you have to stop taking it, you either go cold turkey, risking bizarre withdrawal symptoms and/or worse mental issues, or its a slow taper of weeks to months. Best case scenario you feel dull and blah for a few weeks during that taper. Or you may experience worse symptoms. Either way, it’s a huge waste of time and resources, with a high degree of chance you’ll just say “fuck it” and make a choice that will make things even worse.

      Now imagine repeating that cycle several times over, until you cross whatever arbitrary threshold your local health system deigns is enough suffering to allow them to give you the “treatment resistant” label and open the gates to newer, “non-traditional” treatments with a higher chance of actually working. This magic number of different drugs you have to try can vary based on local laws and your insurance. In my situation, it’s at least 7 different drugs, and you have to try one from each major category. (So 1 SSRI, 1 SNRI, etc…) You also must comply with all your provider’s instructions. If they want you to taper off, you can’t just say “fuck it”, you must take all the scheduled doses until that’s complete. You must be a good obedient patient until whatever authority applies to you decides you’ve had enough.

      There are a few things out there with much higher success rates, like ketamine therapy, MDMA therapy, psylocybin and electroconvulsive therapy (which sounds really scary, but it’s been and continues to be refined and modernized, and currently has a success rate of about 60%, which is considered very good).

      Patients in my area have to survive the drugs gauntlet I’ve described above, plus talk therapy, before they’re allowed to take advantage of the things which medicine already knows are just as safe and vastly more effective - it’s really fucked. Many don’t come out better on the other side of that process, which can take YEARS, and some don’t survive. The only exceptions to this are of course wealthy people who can just end-run around most of the rules because they have the ability to pay directly for the good stuff out of pocket.

      Speaking of money, these treatments which are known to work more often for a greater percentage of people are often a lot more expensive in the short term - if they’re even available where you live. It doesn’t have to be that way but, thanks to regulatory capture, there is a boatload of overhead. These therapies all require licensing, certifications, a higher level of expertise and skill, etc., way way above and beyond just writing a script for, e.g., wellbutrin.

      Because they all work for quite a while after a session, though, you don’t need them as often, and they cost far less in the long run. Sounds good, right? But insurance companies hate things like that. They would much rather you take one or more pills every day for your entire life. They especially like the ones that are difficult to get off of. So they force providers to tinker around with your brain chemistry for a while, with drugs that are just barely effective enough that they continue to be manufactured. They would love for you to give up or die during that phase of treatment, because then they don’t ever have to subsidize those expensive therapies which are more of an occasional appointment or even “one and done” treatment model.

      Some turn to black market sources of ketamine, MDMA or psychs in a desperate attempt to treat themselves, but, naturally, not everyone coloring outside the lines has the knowledge or werewithal to test their drugs or use the correct dose/dosing schedule or provide themselves the proper mindset and environment like a professional would.

      Mental health treatment can be a real wilderness for many.

      • Captain Aggravated@sh.itjust.works
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        8 hours ago

        This is congruent with my own experiences, from which I could draw at least one of two conclusions: 1, the science isn’t done on these medicines. How often outside of psychiatry do you hear “We have to find the cocktail that works for you”? 2, the industry isn’t worthy of caring for patients because money comes before patient care. “This treatment will probably work but so that we can buy a ninth yacht we’ll make you buy all these others first.”

    • TipRing@lemmy.world
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      18 hours ago

      Sertraline was actual torture for me. I stopped sleeping entirely, had constant chills, pounding headache, mood instability where I would just start sobbing for no reason. Started on week 3 and by the end of the week I was begging my doctor to take me off it.

      Sister had similar results. I ended up on different meds.

    • BreadOven@lemmy.world
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      13 hours ago

      Are you daft? It works perfectly fine without side effects for some amount of people. But not nearly everyone.

      I’ve stayed on it because I don’t want to go through the hassle of trial and error with others, but I don’t have that many side effects after many dose modifications.

      It’s asinine to think it works for everyone as intended. Please educate yourself before spouting such bs.

      Also, it’s Sertraline (generic name).

    • LePoisson@lemmy.world
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      19 hours ago

      Took me a few months on sertraline to get back to my horny self and even being able to cum - a frustrating few months indeed - but it helps a ton with the anxiety and eventually I got back to busting nuts so I think it’s worth it.

    • Herbal Gamer@sh.itjust.works
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      16 hours ago

      I take it but went down to the lowest possible dose because my emotions absolutely flatlined. Was great for getting through prison though; day to day just getting through it.

    • ickplant@lemmy.worldOP
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      21 hours ago

      That may be true for SSRIs, but I have bipolar, and I’m on an antipsychotic that also has antidepressant properties. It made me gain hella weight.

    • ayyy@sh.itjust.works
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      18 hours ago

      I gained like 70lbs then lost it all after getting off of them. Losing that much weight while depressed was a bitch and a half.

      • snowdriftissue@lemmy.world
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        18 hours ago

        There is no way that amount of weight gain was caused by an sri. Maybe you were on something else like an atypical/tricyclic antidepressant? Or maybe you were just depressed?