Researchers from Pritzker Molecular Engineering, under the guidance of Prof. Jeffrey Hubbell, demonstrated that their compound can eliminate the autoimmune response linked to multiple sclerosis. Researchers at the University of Chicago’s Pritzker School of Molecular Engineering (PME) have developed

  • MisterChief@lemmy.world
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    2 years ago

    Our immune systems are both one of the most fascinating things about us and for those with autoimmune issues like myself, the most annoying. Always good to see articles like this and I’m glad this focused on the actual science.

    I’d love to sign up for the trial if they ever test it for vitiligo. There are wayyy more serious autoimmune issues that can and should be tested first for those truly suffering. Mine is just “hey look at weird color boy”.

    • stopthatgirl7@kbin.socialOP
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      2 years ago

      Immune systems are wild, and it’s also wild how they can go spectacularly wrong in different ways. Autoimmune diseases run in families, but not necessarily the same disease. My great-aunt has Crohn’s. My dad and big brother both have segmental vitiligo (dad, just on the back of his neck and a shoulder, my brother on one arm), but my immune system decided my thyroid was the enemy. Like. Not fair, body. 🤣

  • scarabic@lemmy.world
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    2 years ago

    I will click on this headline when the link is to Nature or Scientific American or the Mayo Clinic. Thank you very much.

      • scarabic@lemmy.world
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        2 years ago

        Thanks!

        Hm, well the full paper is behind a subscription wall but the abstract sounds much more modest:

        Our findings show that pGal–antigen therapy invokes mechanisms of immune tolerance to resolve antigen-specific inflammatory T-cell responses and suggest that the therapy may be applicable across autoimmune diseases.

        “May be applicable” —> “can completely reverse” ???

  • Jay@sh.itjust.works
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    2 years ago

    My wife has MS. And even though we are of course far from being at a point where the disease will be cured, articles like this give hope.

    There are a lot of smart people who are dealing with the topic. Hopefully they can get something solid done soon!

    • Mog_fanatic@lemmy.world
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      2 years ago

      MS, ALS, and Alzheimer’s are probably the diseases I hope they cure the most at some point. Those 3 are just so ruthless and so hard on everyone. Every time I see something like this I’m super excited but I also feel like I’ve been hearing stuff like this for decades now

      • Mdotaut801@lemmy.world
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        2 years ago

        Psoriatic arthritis recently manifested itself after just struggling with psoriatic nails and a little on my scalp. I’m only 33 and in the mornings I have absolutely 0 fine motor skills and it’s difficult to do things like unlock my front door when I leave for work. Painful as well. My dermatologist referred me to a rheumatologist….1 year for an appointment. No joke.

        • chrizl@lemmy.world
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          2 years ago

          I hope you get help soon!

          I had large amount of psoriasis spots on my arms and legs and also developed arthritis and for me Humira helped immensely.

          No more pain and spots.

  • Apollonius_Cone@lemmy.world
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    2 years ago

    It’s tough to see promising treatments and cures for Type 1. There have been huge inroads for treatment but a cure always seems just around the corner. Here’s to hope for all the Type 1’s and thank you for all the people looking to find that cure.

    • PickTheStick@lemmy.world
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      2 years ago

      Lol, just around the corner is right. My doctor, waaaay back in the 90s, said a cure was 10-15 years away. I think it’s just language they use. Especially when they are talking to the extremely sick/depressed who just learned what they have.

      • Corkyskog@sh.itjust.works
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        2 years ago

        It usually is that close, but that’s assuming unlimited funding… Imagine if anything else had the funding that COVID did.

  • Lakes@lemmy.world
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    2 years ago

    I have MS, I’ll go wild once I hear it’s approved. Until then I’ll save my energy.

  • DontTreadOnBigfoot@lemmy.world
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    2 years ago

    My wife has Type 1 diabetes and I have UC.

    This would be a god-send, but Im not gonna hold my breath. Good news is always a lie.

    • Zanshi@lemmy.world
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      2 years ago

      I’ve had Type 1 Diabetes since I was 6. It’s always 20 years away. I’m 32 now.

    • satrunalia44@lemmy.world
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      2 years ago

      Very often, headlines about new, revolutionary medical breakthroughs actually do result in breakthrough treatments for specific niche disease scenarios. For instance, cancer deaths are down roughly 1/3 over the past 30 years.

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    2 years ago

    “an inverse vaccine”

    Oh good, at least they didn’t choose a name that’s gonna cause confusion.

    TIL you can wait until you have the disease to take the vaccine. So if my kid gets polio, I’ll give them the vaccine then, but I don’t want to risk anything bad happening so I’ll wait. I’m glad I did my research.

    • theragu40@lemmy.world
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      2 years ago

      Treatment. The word they are looking for is treatment.

      I swear to god these research firms absolutely need to get ahead of how they refer to this shit publicly. People are way too dumb to just speak literally.

  • NGC2346@sh.itjust.works
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    2 years ago

    As someone with Celiac disease with a women who also is celiac, this gives so much hope of living a normal life again.

    Please happen !

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      2 years ago

      … initial phase I safety trials have already been carried out in people with celiac disease …

      In case you happened to miss that part. Good luck!

  • WeebLife@lemmy.world
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    2 years ago

    This is really amazing if true. They should not call it a vaccine or else hardly anyone will get it…

    • squiblet@kbin.social
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      I doubt that people suffering from MS, T1, Crohn’s, Celiac etc would be discouraged by the term. It’s not a prophylactic vaccine intended for the general population.

      • WeebLife@lemmy.world
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        2 years ago

        Lol I know that. I’m saying that there are more people than ever that are immediately wary of anything that is called a vaccine. You’re probably right that the ppl this directly impacts wouldn’t think the government put micro chips in it.